Our Partners
Supported by industry leaders
The bottleneck isn’t ideas. It’s search.
Modern discovery has no shortage of targets- genetics, multi-omics, and biology keep expanding the list. The constraint is what happens next: finding and validating small-molecule binders remains slow, expensive, and biased toward familiar libraries and well-characterized proteins. As a result, teams explore only a small fraction of possible protein–molecule combinations, and many high-value targets stay out of reach.
ProPhet changes the economics of hit-finding by turning it into a fast, datalight search problem. We map proteins and small molecules into a shared interaction space so researchers can screen at massive scale and prioritize promising interactions, without waiting on solved structures or assembling large experimental datasets. The result: faster paths from target to actionable hits, and a larger reachable target universe.
Our Focus
Small Molecules
The foundation of most modern drugs, offering precision, scalability, and proven therapeutic value.
Unknown Protein Structures
Less than half of all known proteins lack structural data, presenting untapped opportunities for drug discovery.
AI-Driven Discovery
Combining computational biology with machine learning to uncover new interactions and accelerate drug development.
Why Prophet?
ProPhet analyzes massive chemical libraries with unmatched speed, increasing diversity posibilities, reducing discovery from years to weeks.
Agility – Adapt fast, pivot faster:
Our lightweight models adjust quickly to new targets without costly retraining or delays.
Built for the Hard-to-Drug – Go where others can’t:
We tackle dark, complex proteins that remain elusive to traditional methods, unlocking new therapeutic potential.
Accuracy Without Complexity – Smarter inputs, stronger outcomes:
Just a protein and ligand sequence, no giant datasets or prep needed for powerful predictions.
Designed to Deliver – From prediction to pipeline:
We support both pharma partnerships and in-house development to generate near, and long-term value.